![]() Hormonal therapies consisting of GnRH agonists (histrelin, goserelin, leuprolide) may be effective for some women with depressed moods due to PMDD. ![]() However, women with somatic symptoms like fatigue typically need daily medication treatment with antidepressants. Women who experience mood symptoms related to PMDD usually respond well to luteal-phase dosing. Intermittent dosing (also called luteal-phase dosing) of antidepressants takes place at the same time as the approximately 14-day period from ovulation to menstruation. Instead, some women can take the antidepressant around the time of their menstrual cycles only. This means that women with PMDD do not necessarily have to take the antidepressant every day. These drugs can alleviate the PMDD symptoms faster than they can alleviate symptoms of depression. The first line of treatment for premenstrual dysphoric disorder (PMDD) is an antidepressant medication. ![]() What medications are best for PMDD? Antidepressants To be qualified as PMDD, mood and physical symptoms should be severe enough to interfere with daily life.īefore making a diagnosis of premenstrual dysphoric disorder, it is important to rule out other mental health conditions that can cause similar symptoms, such as major depressive disorder, anxiety, dysthymic disorder (persistent depressive symptoms), chronic fatigue syndrome, and hypothyroidism (underactive thyroid gland). In general, a person is diagnosed with PMDD if they experience five or more PMS symptoms, with at least one mood-related symptom, and those symptoms have occurred with most menstrual cycles during the past year. It can be challenging to differentiate between mild premenstrual symptoms (which, while annoying, are not disabling) and PMDD symptoms that are severe enough to interfere with daily functioning. Experts say risk factors for PMDD include a genetic predisposition as well as stress, obesity, and a history of sexual abuse or trauma. ![]() It is unclear why some women develop PMDD while others do not. What are PMDD symptoms?Īs mentioned, premenstrual dysphoric disorder (PMDD) is a type of severe PMS. Other physical symptoms can include fatigue, decreased energy, joint or muscle pain, headache, breast tenderness, fluid retention, bloating, and diarrhea or constipation. They occur due to the fluctuating levels of ovarian hormones, which affect the functioning of neurotransmitters (chemicals in the brain that influence mood).Ĭommon symptoms of PMS include depressive symptoms, mood swings, crying spells, insomnia, appetite changes, trouble concentrating, social withdrawal, and changes in libido. Many women of childbearing age experience PMS symptoms. What are the symptoms of premenstrual syndrome? Please continue reading to learn more about the medications used to treat PMDD. ![]() Fortunately, effective treatment options are available for premenstrual dysphoric disorder. Severe PMDD symptoms can cause considerable mental distress and disrupt everyday life. Patients with PMDD experience severe, disabling symptoms that affect their ability to work and function on a daily basis. However, up to 10% of women experience a more severe form of PMS called premenstrual dysphoric disorder (PMDD). PMS symptoms are quite common and do not significantly impact a woman’s daily life. Approximately 80% of menstruating women experience PMS (premenstrual syndrome), a constellation of physical and psychological symptoms that occur during the luteal phase of the menstrual cycle (just after the ovary releases the egg and before the menstrual period starts). ![]()
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